What are Symptoms of Smallpox?

Symptoms of smallpox can include head and body aches, a high fever, vomiting, and a rash that spreads and forms bumps that crust and scab. There are two types of smallpox and are called variola major and variola minor. Variola major is the most severe and has a fatality rate of up to 3 percent in people who have been vaccinated. If you have not been vaccinated, the fatality rate can be as high as 50 percent.