Cold sores, often known as fever blisters, should be kept clean at all times. They are highly contagious, so avoid kissing or other activities that may put another person in contact with the cold sore. Taking an antiviral medication can speed up the healing process. To help ease the pain, you could use and over-the-counter cold sore cream. Most importantly, be patient and don’t pick or squeeze the sores and this will only slow the healing process.